Usage
This combination of ingredients is primarily used as a dietary supplement to improve sperm parameters in men with idiopathic infertility. It is not classified as a drug in the traditional sense (e.g., antibiotic, analgesic) but rather as a nutritional supplement. Its mechanism of action involves providing nutritional support to enhance spermatogenesis and improve sperm quality.
Alternate Names
There is no official alternate name for this specific combination. It is often referred to by brand names. One example mentioned in the sources is “Maxoza-L Powder.” Other similar formulations may exist with slight variations in composition or brand names, such as “EDLAR FORTE Sachet” and “Q LARQ FORT SACHET.”
How It Works
Pharmacodynamics: This combination exerts its effects through the synergistic action of its components. L-carnitine facilitates fatty acid transport into mitochondria, promoting energy production for sperm motility. Coenzyme Q10 acts as an antioxidant, protecting sperm from oxidative stress. Folic acid, methylcobalamin (vitamin B12), selenium, and zinc are essential for DNA synthesis, cell division, and sperm maturation. Fructo-oligosaccharides act as prebiotics, supporting gut health, which may indirectly impact fertility. Citric acid is included to enhance palatability.
Pharmacokinetics: The individual components have varying pharmacokinetic profiles. L-carnitine is absorbed in the small intestine and distributed widely. Coenzyme Q10 is absorbed with lipids and undergoes hepatic metabolism. Folic acid is metabolized in the liver. Methylcobalamin is stored in the liver. Selenium is incorporated into selenoproteins. Zinc is absorbed and bound to plasma proteins. Fructo-oligosaccharides are fermented by gut bacteria. Citric acid is readily metabolized. Elimination pathways also vary depending on the individual component (renal/hepatic).
Mode of Action: The ingredients collectively support sperm production and function. CoQ10 protects against oxidative damage. L-carnitine supports energy production. Folic acid, B12, zinc, and selenium participate in DNA synthesis and cell division.
Dosage
Dosage information is not consistently provided across all sources. Some sources suggest the following composition per sachet: Levo-carnitine (1.5gm), Fructo Oligosaccharide (1gm), Coenzyme Q10 (100mg), Citric Acid (50mg), Folic Acid (500mcg or 500mg), Methylcobalamin (2.5mcg), Selenium (50mcg), and Zinc (10mg). Specific dosage guidelines for different age groups or clinical scenarios are not clearly defined in the available sources. One study mentioned participants using a similar combination twice daily for 6 months.
Standard Dosage
Not clearly defined in available sources.
Clinical Use Cases
Not specifically indicated for clinical use cases like intubation, surgery, mechanical ventilation, ICU use, or emergency situations. It is primarily used as a dietary supplement for male infertility.
Dosage Adjustments
Insufficient data available to provide specific dosage adjustments. Clinicians should consider individual patient factors and consult relevant literature or expert opinion.
Side Effects
Common Side Effects
Some sources mention potential side effects such as nausea and vomiting.
Rare but Serious Side Effects
No information is available on rare or serious side effects related to this specific combination.
Long-Term Effects
Information on long-term effects is not available in the provided sources.
Adverse Drug Reactions (ADR)
No specific ADRs related to this combination are mentioned in the provided sources.
Contraindications
No specific contraindications are listed in the provided sources. General precautions for individual components should be considered.
Drug Interactions
No specific drug interactions are listed in the provided sources. Clinicians should consider potential interactions based on the individual components.
Pregnancy and Breastfeeding
This combination is intended for use in males with infertility. Information on pregnancy and breastfeeding is not directly relevant.
Drug Profile Summary
The provided sources are insufficient to create a comprehensive drug profile summary. Further research and consultation with relevant resources are necessary.
Popular Combinations
Not applicable.
Precautions
General precautions include assessing for allergies or sensitivities to any of the components. Pre-existing medical conditions should be taken into consideration before recommending this supplement.
FAQs (Frequently Asked Questions)
Q1: What is the recommended dosage for Citric Acid + Coenzyme Q10 + Folic Acid + Fructo Oligosaccharide + Levo-carnitine + Methylcobalamin + Selenium + Zinc?
A: The available sources do not provide clear dosage recommendations for this specific combination. Some sources mention a composition per sachet but not daily dosage or frequency.
Q2: What is the primary use of this combination?
A: It is primarily used as a nutritional supplement to support male fertility, particularly in cases of idiopathic infertility.
Q3: How does this combination improve sperm parameters?
A: The components work synergistically to improve sperm motility, protect against oxidative stress, support sperm maturation, and enhance overall sperm quality.
Q4: Are there any known drug interactions?
A: The sources do not provide specific information on drug interactions. Clinicians should consider potential interactions based on the individual components.
Q5: What are the common side effects?
A: Some sources mention nausea and vomiting as potential side effects, but detailed information on adverse effects is limited.
Q6: Is this combination safe for long-term use?
A: The available sources do not provide information on the safety of long-term use.
Q7: Who should not take this combination?
A: Individuals with known allergies to any of the components should avoid this supplement. Patients with specific medical conditions should consult their physician before use.
Q8: Is this combination a prescription drug?
A: It is typically marketed as a dietary supplement and not a prescription medication.
Q9: How long does it take to see results?
A: One study mentioned participants using a similar combination for 6 months. The time it takes to see results may vary depending on individual factors.
