Usage
This combination is primarily used as a nutritional supplement to support overall health, particularly cardiovascular health, brain function, and healthy aging. It may also be used adjunctively in cases of male infertility. It addresses nutritional deficiencies and helps manage high blood pressure, elevated cholesterol, cognitive decline, and age-related vision loss. It does not belong to a single pharmacological classification, as it is a combination of nutritional supplements.
The mechanism of action involves synergistic effects of the individual components. Coenzyme Q10 is essential for cellular energy production and acts as an antioxidant. Docosahexanoic acid (DHA) and Eicosapentaenoic acid (EPA) are omega-3 fatty acids crucial for brain health and with anti-inflammatory effects. Lycopene, a potent antioxidant, protects cells from free radical damage. Selenium supports antioxidant enzyme function.
Alternate Names
This combination doesn’t have a standard international nonproprietary name. It is often referred to by its component names or brand names, which can vary depending on the manufacturer. Some examples of brand names include Enerj Q, COQFINE, and SISCUTEN. Other brand names may also exist.
How It Works
Pharmacodynamics: The combined effects result from the individual actions of each component. CoQ10 enhances cellular energy production and acts as an antioxidant. DHA and EPA support brain health, reduce inflammation, and improve cardiovascular health. Lycopene provides antioxidant protection. Selenium enhances the activity of antioxidant enzymes.
Pharmacokinetics: Absorption, metabolism, and elimination vary for each component. CoQ10 absorption is enhanced by fats and can be affected by certain medications. DHA and EPA are metabolized in the liver. Lycopene absorption is improved with dietary fats. Selenium is excreted primarily in urine. Specific details about receptor binding, enzyme inhibition, or neurotransmitter modulation for this combination are not available. Elimination pathways are primarily hepatic and renal.
Dosage
Dosage guidelines are not universally standardized and can vary based on the product formulation and individual needs. A healthcare professional should determine the appropriate dosage.
Standard Dosage
No standardized dosage exists. A doctor should determine the appropriate dosage.
Adults:
Dosage varies depending upon the formulation.
Children:
Not typically recommended for children or adolescents.
Special Cases:
Dosage adjustments should be based on patient-specific factors such as renal/hepatic function and should be determined by a healthcare professional.
Clinical Use Cases
No specific dosage recommendations exist for clinical settings like intubation, surgical procedures, mechanical ventilation, ICU use, or emergency situations.
Dosage Adjustments
Adjustments may be needed based on hepatic or renal impairment or other individual factors. A doctor should make these adjustments.
Side Effects
Common Side Effects
- Digestive upset (diarrhea, nausea, heartburn)
- Fishy burps (due to omega-3 fatty acids)
- Skin discoloration (due to lycopene)
- Headache
Rare but Serious Side Effects
Limited information is available on rare or serious side effects.
Long-Term Effects
Limited information is available on long-term effects.
Adverse Drug Reactions (ADR)
Limited information is available on clinically significant ADRs.
Contraindications
- Known allergies to any of the components.
- Bleeding disorders or those on anticoagulant therapy (due to increased bleeding risk with DHA and EPA).
Drug Interactions
- Blood thinners (e.g., warfarin, aspirin)
- Statins (e.g., atorvastatin, rosuvastatin)
- Antihypertensives (e.g., lisinopril, losartan)
- Some chemotherapy medications (e.g., doxorubicin)
- Alcohol should be avoided or limited.
Pregnancy and Breastfeeding
Safety during pregnancy and breastfeeding isn’t fully established. Consult a doctor before use.
Drug Profile Summary
- Mechanism of Action: See above.
- Side Effects: See above.
- Contraindications: See above.
- Drug Interactions: See above.
- Pregnancy & Breastfeeding: Consult a physician.
- Dosage: Determined by the physician.
- Monitoring Parameters: Blood pressure, coagulation profile (if on blood thinners), liver and kidney function tests (if necessary).
Popular Combinations
No established “popular combinations” exist. Each ingredient has its own potential combinations.
Precautions
- Pre-existing medical conditions (especially heart, liver, or kidney disease)
- Pregnancy and breastfeeding
- Concomitant medications
FAQs (Frequently Asked Questions)
Q1: What is the recommended dosage for Coenzyme Q10 + Docosahexanoic Acid + Eicosapentaenoic Acid + Lycopene + Selenium dioxide?
A: There is no standardized dosage for this combination. A healthcare provider should determine the appropriate dosage based on individual needs and the specific product formulation.
Q2: Is this combination safe during pregnancy?
A: The safety of this combination during pregnancy and breastfeeding isn’t fully established. Consult with a doctor before using this supplement during pregnancy or breastfeeding.
Q3: What are the common side effects?
A: Common side effects may include digestive upset, fishy burps, skin discoloration, and headaches.
Q4: Can I take this combination with blood thinners?
A: This combination may interact with blood thinners. Consult your doctor before taking it if you are on anticoagulant therapy.
Q5: Are there any contraindications for this combination?
A: This combination is contraindicated in individuals with known allergies to any of the components and those with bleeding disorders or on anticoagulant therapy.
Q6: Does this combination interact with any other medications?
A: It may interact with statins, antihypertensive medications, and some chemotherapy drugs. It’s crucial to discuss all medications and supplements you’re taking with your doctor.
Q7: Should any specific parameters be monitored while taking this combination?
A: Monitoring may include blood pressure, coagulation profile (if on blood thinners), and liver and kidney function tests, as deemed necessary by the physician.
Q8: Is this combination a steroid?
A: No, this combination is not a steroid. It is a nutritional supplement.
Q9: What is the mechanism of action of this combination?
A: The components have distinct mechanisms: CoQ10 aids energy production and acts as an antioxidant. DHA and EPA support brain health and have anti-inflammatory effects. Lycopene is an antioxidant. Selenium supports antioxidant enzyme function.
