Usage
This combination of ingredients is primarily used as a dietary supplement to support male fertility and overall health. It is often prescribed for men with fertility issues like low sperm count or motility. It may also be used to address general nutritional deficiencies. While each component has individual pharmacological classifications, the combination itself doesn’t fall neatly into one category. It acts as an antioxidant, supports energy production, and potentially improves circulatory health.
Alternate Names
This specific combination doesn’t have a universally recognized international nonproprietary name (INN). It’s usually referred to by its constituent ingredients. Brand names vary depending on the manufacturer and formulation. One example from the source is “Fertcare M”. Aciq is also a mentioned brand, but the formulation is slightly different.
How It Works
Pharmacodynamics:
- Coenzyme Q10: Acts as an antioxidant and participates in mitochondrial electron transport chain, crucial for cellular energy production.
- L-Arginine: Precursor to nitric oxide, promoting vasodilation and potentially improving blood flow. May also play a role in spermatogenesis.
- Levo-carnitine: Facilitates fatty acid transport into mitochondria for energy production. Important for sperm motility and function.
- Lycopene: Antioxidant, protecting cells from oxidative stress.
- Methylcobalamin: Active form of vitamin B12, crucial for nerve function, DNA synthesis, and red blood cell production.
- Selenium: Essential trace mineral with antioxidant properties. Important for sperm health and motility.
- Vitamin E: Antioxidant, protecting cell membranes from damage.
- Zinc: Essential mineral for reproductive health, supporting testosterone production and sperm development.
Pharmacokinetics:
The individual components have different absorption, metabolism, and elimination profiles. Generally, these components are absorbed through the gastrointestinal tract. Metabolism varies, with some components undergoing hepatic metabolism. Elimination pathways involve both renal and hepatic routes. The exact pharmacokinetic interaction of the combined formulation is not explicitly studied.
Dosage
The dosage of this combination is not standardized and varies depending on the specific product formulation.
Standard Dosage
Adults:
One source suggests one to two tablets daily with a meal. However, this is specific to “Fertcare M” and may not be applicable to all formulations. Always refer to the manufacturer’s instructions for the particular product.
Children:
This combination is typically not recommended for children unless specifically prescribed by a physician.
Special Cases:
Dosage adjustments may be necessary in patients with renal or hepatic impairment, or other underlying medical conditions. Consult a healthcare professional for individualized recommendations.
Clinical Use Cases
The provided sources do not indicate specific dosage recommendations for clinical settings such as intubation, surgical procedures, mechanical ventilation, or ICU use.
Dosage Adjustments
Dose adjustments are typically based on the individual components’ pharmacokinetics and the patient’s specific condition. Consider renal and hepatic function when adjusting dosage.
Side Effects
Common Side Effects
Potential side effects, depending on the specific formulation and individual sensitivity to ingredients, can include gastrointestinal issues (nausea, upset stomach), headache, dizziness, sleep disturbances.
Rare but Serious Side Effects
Severe adverse reactions are rare but possible. Allergic reactions can occur.
Long-Term Effects
Long-term effects are generally not expected with this combination, but individual components, if taken in high doses for extended periods, might pose some risks.
Adverse Drug Reactions (ADR)
Clinically significant ADRs are rare with this combination at recommended dosages.
Contraindications
Contraindications are based primarily on individual sensitivities to ingredients. Certain medical conditions might warrant caution or contraindicate the use of specific components.
Drug Interactions
Potential interactions exist, mostly related to individual components interacting with other drugs. Coenzyme Q10 might interact with anticoagulants. L-arginine can interact with blood pressure medications.
Pregnancy and Breastfeeding
The safety of this combination during pregnancy and breastfeeding hasn’t been fully established. Consulting a doctor is essential before using it during these periods.
Drug Profile Summary
- Mechanism of Action: Antioxidant, supports energy production, improves circulation (potentially).
- Side Effects: Generally mild (GI upset, headache, dizziness).
- Contraindications: Hypersensitivity to any of the components.
- Drug Interactions: Potential interactions with anticoagulants and antihypertensives.
- Pregnancy & Breastfeeding: Consult a physician before use.
- Dosage: Varies depending on formulation; typically 1-2 tablets daily for adults.
- Monitoring Parameters: Semen analysis (if used for male infertility).
Popular Combinations
This combination itself is a “popular combination” for male fertility. Additional medications might be prescribed based on the specific cause of infertility.
Precautions
Standard precautions apply, including assessment for allergies or sensitivities. Caution should be exercised in patients with pre-existing medical conditions.
FAQs (Frequently Asked Questions)
Q1: What is the recommended dosage for Coenzyme Q10 + L-Arginine + Levo-carnitine + Lycopene + Methylcobalamin + Selenium + Vitamin E + Zinc?
A: The dosage varies depending on the specific product. Consult the manufacturer’s instructions or a healthcare professional for guidance.
Q2: Can this combination be used by women trying to conceive?
A: The provided sources primarily focus on male infertility. Consult a physician for recommendations regarding female fertility.
Q3: Are there any dietary restrictions while taking this supplement?
A: No specific dietary restrictions are mentioned in the provided sources, but a balanced healthy diet is always recommended.
Q4: How long does it take to see results?
A: The timeframe for observable effects varies depending on the individual and the specific condition being addressed.
Q5: Can this combination replace a healthy lifestyle?
A: No. Supplements are intended to complement, not replace, a healthy lifestyle.
Q6: Are there any known interactions with alcohol?
A: The sources do not mention specific interactions with alcohol, but moderation is always advisable.
Q7: Can I take this supplement with other medications?
A: Potential drug interactions exist. Inform your doctor about all other medications you are taking.
Q8: Can I crush or chew the tablets?
A: Unless specifically indicated by the manufacturer, swallow the tablets whole.
Q9: What should I do if I miss a dose?
A: If you miss a dose, take it as soon as you remember, unless it’s close to your next scheduled dose. Do not double the dose.
